Experimental Evolution

A collection of articles published in Nature Ecology & Evolution to accompany the June 2020 editorial.
Experimental Evolution

Fundamental evolutionary biology

Antagonistic pleiotropy conceals molecular adaptations in changing environments

Single nucleotide mapping of trait space reveals Pareto fronts that constrain adaptation

Gene amplification as a form of population-level gene expression regulation

Epigenetic gene silencing alters the mechanisms and rate of evolutionary adaptation

Adaptive transcription-splicing resynchronization upon losing an essential splicing factor

Chance and necessity in the pleiotropic consequences of adaptation for budding yeast

The dynamics of adaptive genetic diversity during the early stages of clonal evolution

Altered access to beneficial mutations slows adaptation and biases fixed mutations in diploids

Adaptive evolution by spontaneous domain fusion and protein relocalization

Chromosomal barcoding of E. coli populations reveals lineage diversity dynamics at high resolution

Collective motion conceals fitness differences in crowded cellular populations

Sex alters molecular evolution in diploid experimental populations of S. cerevisiae

Microbial life cycles link global modularity in regulation to mosaic evolution

Dual-stressor selection alters eco-evolutionary dynamics in experimental communities

Antimicrobial resistance

Multicopy plasmids potentiate the evolution of antibiotic resistance in bacteria

Coevolution of host–plasmid pairs facilitates the emergence of novel multidrug resistance

Identifying and exploiting genes that potentiate the evolution of antibiotic resistance

Compensatory mutations improve general permissiveness to antibiotic resistance plasmids

Adaptive modulation of antibiotic resistance through intragenomic coevolution

The unconstrained evolution of fast and efficient antibiotic-resistant bacterial genomes

Drug-mediated metabolic tipping between antibiotic resistant states in a mixed-species community

Positive selection inhibits gene mobilization and transfer in soil bacterial communities

Global Change

Rapid evolution of highly variable competitive abilities in a key phytoplankton species 

Community rescue in experimental phytoplankton communities facing severe herbicide pollution

Adaptation of phytoplankton to a decade of experimental warming linked to increased photosynthesis


Fibroblasts and alectinib switch the evolutionary games played by non-small cell lung cancer