William Cross

Postdoctoral Researcher, University College London Cancer Institute
  • University College London Cancer Institute
  • United Kingdom

About William Cross

My specialist interests include somatic evolution, cancer genetics, and computational biology. My work explores the selection forces acting on somatic cell karyotypes, with aim to understand the fundamentals of cancer growth. I am currently a Research Fellow, a writer, and an associate editor at the Journal of Pathology.


Ecological genetics Evolutionary theory Phylogenetics

Intro Content


Getting a handle on the evolutionary processes of cancer

The methodologies that we use to study cancer are ever changing. In recent years researchers have aligned pathological evidences alongside classical evolutionary theory and with this comes both opportunities and challenges. Here I discuss a practical challenge that underlies our recent paper "The evolutionary landscape of colorectal tumorigenesis", which was how to acquire and process samples from pre-malignant lesions. I also note a particularly surprising result, which could only have been gleaned through an evolutionary directed analysis on the resulting data.

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